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Heterologous Production of the Lantibiotic Ala(0)Actagardine in Escherichia coli()
We report the heterologous production of Ala(0)actagardine in E. coli by co-expression of the substrate peptide GarA and its modification enzymes GarM and GarO. The activity of GarO, a luciferase-like monooxygenase that introduces the unique sulfoxide group of actagardine, was also investigated in v...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3485686/ https://ncbi.nlm.nih.gov/pubmed/23034674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc36336d |
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