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Multimodality Imaging of Coiled-Coil Mediated Self-Assembly in a “Drug Free” Therapeutic System
We used two complementary coiled-coil peptides CCE/CCK to develop a “drug free” therapeutic system, which can specifically kill cancer cells without a drug. CCE was attached to the Fab’ fragment of anti-CD20 1F5 antibody (Fab’-CCE), and CCK was conjugated in multiple grafts to poly[N-(2-hydroxypropy...
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| Pubblicato in: | Adv Healthc Mater |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433428/ https://ncbi.nlm.nih.gov/pubmed/25612325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400679 |
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