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Multimodality Imaging of Coiled-Coil Mediated Self-Assembly in a “Drug Free” Therapeutic System

We used two complementary coiled-coil peptides CCE/CCK to develop a “drug free” therapeutic system, which can specifically kill cancer cells without a drug. CCE was attached to the Fab’ fragment of anti-CD20 1F5 antibody (Fab’-CCE), and CCK was conjugated in multiple grafts to poly[N-(2-hydroxypropy...

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Dades bibliogràfiques
Publicat a:Adv Healthc Mater
Autors principals: Zhang, Rui, Yang, Jiyuan, Chu, Te-Wei, Hartley, Jonathan M., Kopeček, Jindřich
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433428/
https://ncbi.nlm.nih.gov/pubmed/25612325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400679
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