Fetal consequences of maternal antiretroviral nucleoside reverse transcriptase inhibitor (NRTI) use in human and non-human primate pregnancy

PURPOSE OF REVIEW: Here we present fetal genotoxicity and mitochondrial toxicity, induced by NRTIs, in HIV-1-infected pregnant women treated to prevent mother-to-child HIV-1 transmission (MTCT), and in virus-free pregnant patas monkeys. RECENT FINDINGS: In offspring of pregnant patas monkeys given h...

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Bibliographic Details
Published in:Curr Opin Pediatr
Main Authors: Poirier, Miriam C., Gibbons, Alexander T., Rugeles, Maria T., Andre-Schmutz, Isabelle, Blanche, Stephane
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433159/
https://ncbi.nlm.nih.gov/pubmed/25635584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOP.0000000000000193
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