Tempol Protects Cardiomyocytes from Nucleoside Reverse Transcriptase Inhibitor-Induced Mitochondrial Toxicity

Nucleoside reverse transcriptase inhibitors (NRTIs), essential components of combinational therapies used for treatment of human immunodeficiency virus-1, damage heart mitochondria. Here, we have shown mitochondrial compromise in H9c2 rat cardiomyocytes exposed for 16 passages (P) to the NRTIs zidov...

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Detalhes bibliográficos
Main Authors: Liu, Yongmin, Shim, Eunwoo, Nguyen, Phuonggiang, Gibbons, Alexander T., Mitchell, James B., Poirier, Miriam C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Molecular Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999381/
https://ncbi.nlm.nih.gov/pubmed/24591154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu034
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