Progressive Mitochondrial Compromise in Brains and Livers of Primates Exposed In Utero to Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

Mitochondrial compromise has been documented in infants born to women infected with the human immunodeficiency virus (HIV-1) who received nucleoside reverse transcriptase inhibitor (NRTI) therapy during pregnancy. To model these human exposures, we examined mitochondrial integrity at birth and 1 yea...

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Detalhes bibliográficos
Main Authors: Divi, Rao L., Einem, Tracey L., Leonard Fletcher, Sarah L., Shockley, Marie E., Kuo, Maryanne M., St Claire, Marisa C., Cook, Anthony, Nagashima, Kunio, Harbaugh, Steven W., Harbaugh, Jeffrey W., Poirier, Miriam C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Reproductive and Developmental Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955212/
https://ncbi.nlm.nih.gov/pubmed/20702595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq235
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