In Vitro Cross-Resistance Profile of Nucleoside Reverse Transcriptase Inhibitor (NRTI) BMS-986001 against Known NRTI Resistance Mutations

BMS-986001 is a novel HIV nucleoside reverse transcriptase inhibitor (NRTI). To date, little is known about its resistance profile. In order to examine the cross-resistance profile of BMS-986001 to NRTI mutations, a replicating virus system was used to examine specific amino acid mutations known to...

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Detalhes bibliográficos
Main Authors: Li, Zhufang, Terry, Brian, Olds, William, Protack, Tricia, Deminie, Carol, Minassian, Beatrice, Nowicka-Sans, Beata, Sun, Yongnian, Dicker, Ira, Hwang, Carey, Lataillade, Max, Hanna, George J., Krystal, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811251/
https://ncbi.nlm.nih.gov/pubmed/23979732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01195-13
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