Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6

The cGMP phosphodiesterase of rod photoreceptor cells, PDE6, is the key effector enzyme in phototransduction. Two large catalytic subunits, PDE6α and -β, each contain one catalytic domain and two non-catalytic GAF domains, whereas two small inhibitory PDE6γ subunits allow tight regulation by the G p...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Zhang, Zhixian, He, Feng, Constantine, Ryan, Baker, Matthew L., Baehr, Wolfgang, Schmid, Michael F., Wensel, Theodore G., Agosto, Melina A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432299/
https://ncbi.nlm.nih.gov/pubmed/25809480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.647636
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items