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Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel
Small GTPases alternatively bind GDP/GTP guanine nucleotides to gate signaling pathways that direct most cellular processes. Numerous GTPases are implicated in oncogenesis, particularly the three RAS isoforms HRAS, KRAS, and NRAS and the RHO family GTPase RAC1. Signaling networks comprising small GT...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6597838/ https://ncbi.nlm.nih.gov/pubmed/31088913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008653 |
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