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Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel

Small GTPases alternatively bind GDP/GTP guanine nucleotides to gate signaling pathways that direct most cellular processes. Numerous GTPases are implicated in oncogenesis, particularly the three RAS isoforms HRAS, KRAS, and NRAS and the RHO family GTPase RAC1. Signaling networks comprising small GT...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Killoran, Ryan C., Smith, Matthew J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597838/
https://ncbi.nlm.nih.gov/pubmed/31088913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008653
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