Impact of Antimalarial Treatment and Chemoprevention on the Drug Sensitivity of Malaria Parasites Isolated from Ugandan Children

Changing treatment practices may be selecting for changes in the drug sensitivity of malaria parasites. We characterized ex vivo drug sensitivity and parasite polymorphisms associated with sensitivity in 459 Plasmodium falciparum samples obtained from subjects enrolled in two clinical trials in Toro...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Tumwebaze, Patrick, Conrad, Melissa D., Walakira, Andrew, LeClair, Norbert, Byaruhanga, Oswald, Nakazibwe, Christine, Kozak, Benjamin, Bloome, Jessica, Okiring, Jaffer, Kakuru, Abel, Bigira, Victor, Kapisi, James, Legac, Jennifer, Gut, Jiri, Cooper, Roland A., Kamya, Moses R., Havlir, Diane V., Dorsey, Grant, Greenhouse, Bryan, Nsobya, Samuel L., Rosenthal, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432194/
https://ncbi.nlm.nih.gov/pubmed/25753626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05141-14
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