Polymorphisms in K13 and Falcipain-2 Associated with Artemisinin Resistance Are Not Prevalent in Plasmodium falciparum Isolated from Ugandan Children

The emergence of resistance to artemisinin derivatives in Southeast Asia, manifested as delayed clearance of Plasmodium falciparum following treatment with artemisinins, is a major concern. Recently, the artemisinin resistance phenotype was attributed to mutations in portions of a P. falciparum gene...

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Main Authors: Conrad, Melissa D., Bigira, Victor, Kapisi, James, Muhindo, Mary, Kamya, Moses R., Havlir, Diane V., Dorsey, Grant, Rosenthal, Philip J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140830/
https://ncbi.nlm.nih.gov/pubmed/25144768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105690
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