Polymorphisms in K13 and Falcipain-2 Associated with Artemisinin Resistance Are Not Prevalent in Plasmodium falciparum Isolated from Ugandan Children

The emergence of resistance to artemisinin derivatives in Southeast Asia, manifested as delayed clearance of Plasmodium falciparum following treatment with artemisinins, is a major concern. Recently, the artemisinin resistance phenotype was attributed to mutations in portions of a P. falciparum gene...

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Main Authors: Conrad, Melissa D., Bigira, Victor, Kapisi, James, Muhindo, Mary, Kamya, Moses R., Havlir, Diane V., Dorsey, Grant, Rosenthal, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140830/
https://ncbi.nlm.nih.gov/pubmed/25144768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105690
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