Comparative Impacts Over 5 Years of Artemisinin-Based Combination Therapies on Plasmodium falciparum Polymorphisms That Modulate Drug Sensitivity in Ugandan Children

Background. Artemisinin-based combination therapies, including artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP), are recommended to treat uncomplicated falciparum malaria. Sensitivities to components of AL and DP are impacted by polymorphisms in pfmdr1 and pfcrt. We monitored cha...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Conrad, Melissa D., LeClair, Norbert, Arinaitwe, Emmanuel, Wanzira, Humphrey, Kakuru, Abel, Bigira, Victor, Muhindo, Mary, Kamya, Moses R., Tappero, Jordan W., Greenhouse, Bryan, Dorsey, Grant, Rosenthal, Philip J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2014
Θέματα:
Major Articles and Brief Reports
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110461/
https://ncbi.nlm.nih.gov/pubmed/24610872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu141
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