Comparative Impacts Over 5 Years of Artemisinin-Based Combination Therapies on Plasmodium falciparum Polymorphisms That Modulate Drug Sensitivity in Ugandan Children

Background. Artemisinin-based combination therapies, including artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP), are recommended to treat uncomplicated falciparum malaria. Sensitivities to components of AL and DP are impacted by polymorphisms in pfmdr1 and pfcrt. We monitored cha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Conrad, Melissa D., LeClair, Norbert, Arinaitwe, Emmanuel, Wanzira, Humphrey, Kakuru, Abel, Bigira, Victor, Muhindo, Mary, Kamya, Moses R., Tappero, Jordan W., Greenhouse, Bryan, Dorsey, Grant, Rosenthal, Philip J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Major Articles and Brief Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110461/
https://ncbi.nlm.nih.gov/pubmed/24610872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu141
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