Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice.
Targeted disruption of the c-src proto-oncogene in mice has shown that src expression is required for normal bone resorption, since the src-deficient mutants develop osteopetrosis. To evaluate the mechanisms by which src-deficiency affects osteoclast function, we treated src-deficient mice with the...
Spremljeno u:
| Izdano u: | J Clin Invest |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
1992
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443211/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1383278/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116032 |
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