The IL-33/ST2 axis augments effector T-cell responses during acute GVHD

Interleukin (IL)-33 binding to the receptor suppression of tumorigenicity 2 (ST2) produces pro-inflammatory and anti-inflammatory effects. Increased levels of soluble ST2 (sST2) are a biomarker for steroid-refractory graft-versus-host disease (GVHD) and mortality. However, whether sST2 has a role as...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Reichenbach, Dawn K., Schwarze, Vincent, Matta, Benjamin M., Tkachev, Victor, Lieberknecht, Elisabeth, Liu, Quan, Koehn, Brent H., Pfeifer, Dietmar, Taylor, Patricia A., Prinz, Gabriele, Dierbach, Heide, Stickel, Natalie, Beck, Yvonne, Warncke, Max, Junt, Tobias, Schmitt-Graeff, Annette, Nakae, Susumu, Follo, Marie, Wertheimer, Tobias, Schwab, Lukas, Devlin, Jason, Watkins, Simon C., Duyster, Justus, Ferrara, James L. M., Turnquist, Heth R., Zeiser, Robert, Blazar, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432012/
https://ncbi.nlm.nih.gov/pubmed/25814531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-606830
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