Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD

During allogeneic hematopoietic cell transplantation (alloHCT), nonhematopoietic cell interleukin-33 (IL-33) is augmented and released by recipient conditioning to promote type 1 alloimmunity and lethal acute graft-versus-host disease (GVHD). Yet, IL-33 is highly pleiotropic and exhibits potent immu...

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Bibliografiska uppgifter
I publikationen:Blood
Huvudupphovsmän: Matta, Benjamin M., Reichenbach, Dawn K., Zhang, Xiaoli, Mathews, Lisa, Koehn, Brent H., Dwyer, Gaelen K., Lott, Jeremy M., Uhl, Franziska M., Pfeifer, Dietmar, Feser, Colby J., Smith, Michelle J., Liu, Quan, Zeiser, Robert, Blazar, Bruce R., Turnquist, Hēth R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2016
Ämnen:
Transplantation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957164/
https://ncbi.nlm.nih.gov/pubmed/27222477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-684142
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