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Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD

During allogeneic hematopoietic cell transplantation (alloHCT), nonhematopoietic cell interleukin-33 (IL-33) is augmented and released by recipient conditioning to promote type 1 alloimmunity and lethal acute graft-versus-host disease (GVHD). Yet, IL-33 is highly pleiotropic and exhibits potent immu...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Blood
Päätekijät: Matta, Benjamin M., Reichenbach, Dawn K., Zhang, Xiaoli, Mathews, Lisa, Koehn, Brent H., Dwyer, Gaelen K., Lott, Jeremy M., Uhl, Franziska M., Pfeifer, Dietmar, Feser, Colby J., Smith, Michelle J., Liu, Quan, Zeiser, Robert, Blazar, Bruce R., Turnquist, Hēth R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957164/
https://ncbi.nlm.nih.gov/pubmed/27222477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-684142
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