Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD

The common γ chain (CD132) is a subunit of the interleukin (IL) receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Because levels of several of these cytokines were shown to be increased in the serum of patients developing acute and chronic graft-versus-host disease (GVHD), we reasoned that inh...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Hechinger, Anne-Kathrin, Smith, Benjamin A. H., Flynn, Ryan, Hanke, Kathrin, McDonald-Hyman, Cameron, Taylor, Patricia A., Pfeifer, Dietmar, Hackanson, Björn, Leonhardt, Franziska, Prinz, Gabriele, Dierbach, Heide, Schmitt-Graeff, Annette, Kovarik, Jiri, Blazar, Bruce R., Zeiser, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296017/
https://ncbi.nlm.nih.gov/pubmed/25352130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-581793
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