The IL-33/ST2 axis augments effector T-cell responses during acute GVHD

Interleukin (IL)-33 binding to the receptor suppression of tumorigenicity 2 (ST2) produces pro-inflammatory and anti-inflammatory effects. Increased levels of soluble ST2 (sST2) are a biomarker for steroid-refractory graft-versus-host disease (GVHD) and mortality. However, whether sST2 has a role as...

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Publicat a:Blood
Autors principals: Reichenbach, Dawn K., Schwarze, Vincent, Matta, Benjamin M., Tkachev, Victor, Lieberknecht, Elisabeth, Liu, Quan, Koehn, Brent H., Pfeifer, Dietmar, Taylor, Patricia A., Prinz, Gabriele, Dierbach, Heide, Stickel, Natalie, Beck, Yvonne, Warncke, Max, Junt, Tobias, Schmitt-Graeff, Annette, Nakae, Susumu, Follo, Marie, Wertheimer, Tobias, Schwab, Lukas, Devlin, Jason, Watkins, Simon C., Duyster, Justus, Ferrara, James L. M., Turnquist, Heth R., Zeiser, Robert, Blazar, Bruce R.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Transplantation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432012/
https://ncbi.nlm.nih.gov/pubmed/25814531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-606830
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