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Neuroendocrine Merkel Cell Carcinoma is Associated with Mutations in key DNA Repair, Epigenetic and Apoptosis Pathways: A Case-based Study using targeted Massively Parallel Sequencing
Merkel cell carcinoma (MCC) is a rare neuroendocrine carcinoma with poorly understood molecular etiology. We implemented a comprehensive deep sequencing approach to identify mutations in the tumor DNA from a cohort of patients treated at our institution over the past 15 years. Our results indicate m...
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| Veröffentlicht in: | Neuroendocrinology |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4431917/ https://ncbi.nlm.nih.gov/pubmed/25531179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000370310 |
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