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HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications

Integration of retroviral DNA into host cell DNA is a defining feature of retroviral replication. HIV integration is known to be favored in active transcription units, which promotes efficient transcription of the viral genes, but the molecular mechanisms responsible for targeting are not fully clar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Gary P., Ciuffi, Angela, Leipzig, Jeremy, Berry, Charles C., Bushman, Frederic D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933515/
https://ncbi.nlm.nih.gov/pubmed/17545577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6286907
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