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HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications

Integration of retroviral DNA into host cell DNA is a defining feature of retroviral replication. HIV integration is known to be favored in active transcription units, which promotes efficient transcription of the viral genes, but the molecular mechanisms responsible for targeting are not fully clar...

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Библиографические подробности
Главные авторы: Wang, Gary P., Ciuffi, Angela, Leipzig, Jeremy, Berry, Charles C., Bushman, Frederic D.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933515/
https://ncbi.nlm.nih.gov/pubmed/17545577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6286907
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