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DNA bar coding and pyrosequencing to identify rare HIV drug resistance mutations

Treatment of HIV-infected individuals with antiretroviral agents selects for drug-resistant mutants, resulting in frequent treatment failures. Although the major antiretroviral resistance mutations are routinely characterized by DNA sequencing, treatment failures are still common, probably in part b...

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Detalhes bibliográficos
Main Authors: Hoffmann, Christian, Minkah, Nana, Leipzig, Jeremy, Wang, Gary, Arens, Max Q., Tebas, Pablo, Bushman, Frederic D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934997/
https://ncbi.nlm.nih.gov/pubmed/17576693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm435
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