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HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications

Integration of retroviral DNA into host cell DNA is a defining feature of retroviral replication. HIV integration is known to be favored in active transcription units, which promotes efficient transcription of the viral genes, but the molecular mechanisms responsible for targeting are not fully clar...

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Detalhes bibliográficos
Main Authors: Wang, Gary P., Ciuffi, Angela, Leipzig, Jeremy, Berry, Charles C., Bushman, Frederic D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933515/
https://ncbi.nlm.nih.gov/pubmed/17545577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6286907
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