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Neuroendocrine Merkel Cell Carcinoma is Associated with Mutations in key DNA Repair, Epigenetic and Apoptosis Pathways: A Case-based Study using targeted Massively Parallel Sequencing

Merkel cell carcinoma (MCC) is a rare neuroendocrine carcinoma with poorly understood molecular etiology. We implemented a comprehensive deep sequencing approach to identify mutations in the tumor DNA from a cohort of patients treated at our institution over the past 15 years. Our results indicate m...

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Detalhes bibliográficos
Publicado no:Neuroendocrinology
Main Authors: Graves, Christian A., Jones, Ashley, Reynolds, Justin, Stuart, Jeremy, Pirisi, Lucia, Botrous, Peter, Wells, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431917/
https://ncbi.nlm.nih.gov/pubmed/25531179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000370310
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