Relief of opsin desensitization and prolonged excitation of rod photoreceptors by 9-desmethylretinal.
The 9-methyl group of 11-cis-retinal plays a crucial role in photoexcitation of the visual pigment rhodopsin. A hydrogen-substituted analogue, 11-cis-9-desmethylretinal, combines with opsin to form a pigment that produces abnormal photoproducts and diminished activation of the GTP-binding protein tr...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1994
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44317/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8041729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.6958 |
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