The HSP90 Inhibitor Ganetespib Alleviates Disease Progression and Augments Intermittent Cyclophosphamide Therapy in the MRL/lpr Mouse Model of Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a complex, systemic autoimmune disease with a diverse range of immunological and clinical manifestations. The introduction of broad spectrum immunosuppressive therapies and better management of acute disease exacerbations have improved outcomes for lupus patient...

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Veröffentlicht in:PLoS One
Hauptverfasser: Liu, Yuan, Ye, Josephine, Shin Ogawa, Luisa, Inoue, Takayo, Huang, Qin, Chu, John, Bates, Richard C., Ying, Weiwen, Sonderfan, Andrew J., Rao, Patricia E., Zhou, Dan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431681/
https://ncbi.nlm.nih.gov/pubmed/25974040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127361
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