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Tamoxifen alleviates disease severity and decreases double negative T cells in autoimmune MRL-lpr/lpr mice
Previous study suggested that MRL-lpr/lpr mice treated with tamoxifen (TAM) had less severe proteinuria, reduced serum titre of anti-dsDNA autoantibodies and an increased survival rate. To investigate further the regulatory mechanisms of TAM on MRL-lpr/lpr female mice, a total dose of 200 µg per mic...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2000
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2326982/ https://ncbi.nlm.nih.gov/pubmed/10809966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00998.x |
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