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Eprobe-mediated screening system for somatic mutations in the KRAS locus

Activating mutations in the Kirsten rat sarcoma viral oncogene homolog (KRAS) loci are largely predictive of resistance to epidermal growth factor receptor (EGFR) therapy in colorectal cancer (CRC). A highly sensitive detection system for the KRAS gene mutations is urgently needed; however, conventi...

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Rep
Hauptverfasser: ATSUMI, JUN, HANAMI, TAKESHI, ENOKIDA, YASUAKI, OGAWA, HIROOMI, DELOBEL, DIANE, MITANI, YASUMASA, KIMURA, YASUMASA, SOMA, TAKAHIRO, TAGAMI, MICHIHIRA, TAKASE, YOSHIAKI, ICHIHARA, TATSUO, TAKEYOSHI, IZUMI, USUI, KENGO, HAYASHIZAKI, YOSHIHIDE, SHIMIZU, KIMIHIRO
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431451/
https://ncbi.nlm.nih.gov/pubmed/25823645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2015.3883
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