Highly sensitive detection of a HER2 12-base pair duplicated insertion mutation in lung cancer using the Eprobe-PCR method

Somatic mutation in human epidermal growth factor receptor-related 2 gene (HER2) is one of the driver mutations in lung cancer. HER2 mutations are found in about 2% of lung adenocarcinomas (ADCs). Previous reports have been based mainly on diagnostic screening by Sanger sequencing or next-generation...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Takase, Yoshiaki, Usui, Kengo, Shimizu, Kimihiro, Kimura, Yasumasa, Ichihara, Tatsuo, Ohkawa, Takahiro, Atsumi, Jun, Enokida, Yasuaki, Nakazawa, Seshiru, Obayashi, Kai, Ohtaki, Yoichi, Nagashima, Toshiteru, Mitani, Yasumasa, Takeyoshi, Izumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289711/
https://ncbi.nlm.nih.gov/pubmed/28152008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171225
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