Rapid Detection of SNP (c.309T>G) in the MDM2 Gene by the Duplex SmartAmp Method

BACKGROUND: Genetic polymorphisms in the human MDM2 gene are suggested to be a tumor susceptibility marker and a prognostic factor for cancer. It has been reported that a single nucleotide polymorphism (SNP) c.309T>G in the MDM2 gene attenuates the tumor suppressor activity of p53 and accelerates...

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Autori principali: Enokida, Yasuaki, Shimizu, Kimihiro, Atsumi, Jun, Lezhava, Alexander, Tanaka, Yuki, Kimura, Yasumasa, Soma, Takahiro, Hanami, Takeshi, Kawai, Yuki, Usui, Kengo, Okano, Yasuko, Kakegawa, Seiichi, Ogawa, Hiroomi, Miyamae, Yohei, Miyagi, Yohei, Nakayama, Haruhiko, Ishikawa, Toshihisa, Hayashizaki, Yoshihide, Takeyoshi, Izumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614994/
https://ncbi.nlm.nih.gov/pubmed/23565197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060151
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