Single-nucleotide polymorphism (c.309T>G) in the MDM2 gene and lung cancer risk

Murine double minute 2 (MDM2) is a negative regulator of p53. A single-nucleotide polymorphism (SNP) (rs2279744: c.309T>G) in the promoter region of the MDM2 gene has been shown to result in higher levels of MDM2 RNA and protein. Regarding the contribution of c.309T>G in the MDM2 gene to the l...

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Main Authors: ENOKIDA, YASUAKI, SHIMIZU, KIMIHIRO, KAKEGAWA, SEIICHI, ATSUMI, JUN, TAKASE, YOSHIAKI, MIYAMAE, YOHEI, NAGASHIMA, TOSHITERU, OHTAKI, YOICHI, KAIRA, KYOICHI, SUNAGA, NORIAKI, YANAGITANI, NORIKO, YOSHINO, REIKO, TSUNEKAWA, KATSUHIKO, IGAI, HITOSHI, KAMIYOSHIHARA, MITSUHIRO, USUI, KENGO, LEZHAVA, ALEXANDER, TOMIZAWA, YOSHIO, ISHIKAWA, TOSHIHISA, MURAKAMI, MASAMI, HAYASHIZAKI, YOSHIHIDE, TAKEYOSHI, IZUMI
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106610/
https://ncbi.nlm.nih.gov/pubmed/25054017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2014.305
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