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A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease.

In mice, the two distinct autosomal recessive genes lpr and gld can induce a syndrome characterized by autoantibody formation and the progressive accumulation of an unusual CD4-CD8- T cell population in peripheral lymphoid tissue. This phenotype does not precisely mirror any human disease. In this r...

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Main Authors: Sneller, M C, Straus, S E, Jaffe, E S, Jaffe, J S, Fleisher, T A, Stetler-Stevenson, M, Strober, W
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC443107/
https://ncbi.nlm.nih.gov/pubmed/1386609
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