Загрузка...
Transcriptional changes associated with resistance to inhibitors of epidermal growth factor receptor revealed using metaanalysis
BACKGROUND: EGFR is important in maintaining metabolic homeostasis in healthy cells, but in tumors it activates downstream signaling pathways, causing proliferation, angiogenesis, invasion and metastasis. Consequently, EGFR is targeted in cancers using reversible, irreversible or antibody inhibitors...
Сохранить в:
| Опубликовано в: : | BMC Cancer |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2015
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4430867/ https://ncbi.nlm.nih.gov/pubmed/25948104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1337-3 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|