טוען...
Transcriptional changes associated with resistance to inhibitors of epidermal growth factor receptor revealed using metaanalysis
BACKGROUND: EGFR is important in maintaining metabolic homeostasis in healthy cells, but in tumors it activates downstream signaling pathways, causing proliferation, angiogenesis, invasion and metastasis. Consequently, EGFR is targeted in cancers using reversible, irreversible or antibody inhibitors...
שמור ב:
| הוצא לאור ב: | BMC Cancer |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4430867/ https://ncbi.nlm.nih.gov/pubmed/25948104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1337-3 |
| תגים: |
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