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Differential Transcriptional Effects of EGFR Inhibitors

EGF and its receptor EGFR serve as a paradigm for signaling in cell, molecular and tumor biology. EGFR inhibitors, drugs targeting the intracellular kinase activity and antibodies targeting the extracellular ligand binding, are used to treat breast, lung, colon and other cancers. Nominally affecting...

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Detalhes bibliográficos
Autor principal: Blumenberg, Miroslav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153546/
https://ncbi.nlm.nih.gov/pubmed/25184905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102466
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