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Differential Transcriptional Effects of EGFR Inhibitors

EGF and its receptor EGFR serve as a paradigm for signaling in cell, molecular and tumor biology. EGFR inhibitors, drugs targeting the intracellular kinase activity and antibodies targeting the extracellular ligand binding, are used to treat breast, lung, colon and other cancers. Nominally affecting...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
1. Verfasser: Blumenberg, Miroslav
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153546/
https://ncbi.nlm.nih.gov/pubmed/25184905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102466
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