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Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe

Cyclooxygenase-2 (COX-2) is a promising target for the imaging of cancer in a range of diagnostic and therapeutic settings. We report a near-infrared COX-2-targeted probe, fluorocoxib C (FC), for visualization of solid tumors by optical imaging. FC exhibits selective and potent COX-2 inhibition in b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biomed Opt
Hauptverfasser: Uddin, Md. Jashim, Crews, Brenda C., Ghebreselasie, Kebreab, Daniel, Cristina K., Kingsley, Philip J., Xu, Shu, Marnett, Lawrence J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society of Photo-Optical Instrumentation Engineers 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430360/
https://ncbi.nlm.nih.gov/pubmed/25970082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.20.5.050502
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