Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation.

Platelet activation by thrombin is critical for hemostasis and thrombosis. Structure-function studies with a recently cloned platelet thrombin receptor suggest that a hirudin-like domain in the receptor's extracellular amino terminal extension is a thrombin-binding determinant important for receptor...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	J Clin Invest
Prif Awduron:	Hung, D T, Vu, T K, Wheaton, V I, Ishii, K, Coughlin, S R
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Clinical Investigation 1992
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442997/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115721
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