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Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation.
Platelet activation by thrombin is critical for hemostasis and thrombosis. Structure-function studies with a recently cloned platelet thrombin receptor suggest that a hirudin-like domain in the receptor's extracellular amino terminal extension is a thrombin-binding determinant important for rec...
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| Udgivet i: | J Clin Invest |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1992
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442997/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115721 |
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