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Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation.

Platelet activation by thrombin is critical for hemostasis and thrombosis. Structure-function studies with a recently cloned platelet thrombin receptor suggest that a hirudin-like domain in the receptor's extracellular amino terminal extension is a thrombin-binding determinant important for rec...

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Autors principals: Hung, D T, Vu, T K, Wheaton, V I, Ishii, K, Coughlin, S R
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC442997/
https://ncbi.nlm.nih.gov/pubmed/1313452
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