Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation.

Platelet activation by thrombin is critical for hemostasis and thrombosis. Structure-function studies with a recently cloned platelet thrombin receptor suggest that a hirudin-like domain in the receptor's extracellular amino terminal extension is a thrombin-binding determinant important for receptor...

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מידע ביבליוגרפי

הוצא לאור ב:	J Clin Invest
Principais autores:	Hung, D T, Vu, T K, Wheaton, V I, Ishii, K, Coughlin, S R
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Clinical Investigation 1992
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442997/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115721
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