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Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

Perfusion of the myocardium with protein C in the presence of thrombin (EC 3.4.21.5) elicits a potent anticoagulant activity, which is identified as activated protein C on the basis of synthetic substrate hydrolysis and anticoagulant properties. The rate of activated protein C formation during the t...

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Detalhes bibliográficos
Main Authors: Esmon, C T, Owen, W G
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC319322/
https://ncbi.nlm.nih.gov/pubmed/7017729
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