Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.
Perfusion of the myocardium with protein C in the presence of thrombin (EC 3.4.21.5) elicits a potent anticoagulant activity, which is identified as activated protein C on the basis of synthetic substrate hydrolysis and anticoagulant properties. The rate of activated protein C formation during the t...
Guardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1981
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7017729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2249 |
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