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Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

Perfusion of the myocardium with protein C in the presence of thrombin (EC 3.4.21.5) elicits a potent anticoagulant activity, which is identified as activated protein C on the basis of synthetic substrate hydrolysis and anticoagulant properties. The rate of activated protein C formation during the t...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Esmon, C T, Owen, W G
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1981
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319322/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7017729/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2249
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