Cardiac I-1c Overexpression With Reengineered AAV Improves Cardiac Function in Swine Ischemic Heart Failure

Cardiac gene therapy has emerged as a promising option to treat advanced heart failure (HF). Advances in molecular biology and gene targeting approaches are offering further novel options for genetic manipulation of the cardiovascular system. The aim of this study was to improve cardiac function in...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Ishikawa, Kiyotake, Fish, Kenneth M, Tilemann, Lisa, Rapti, Kleopatra, Aguero, Jaume, Santos-Gallego, Carlos G, Lee, Ahyoung, Karakikes, Ioannis, Xie, Chaoqin, Akar, Fadi G, Shimada, Yuichi J, Gwathmey, Judith K, Asokan, Aravind, McPhee, Scott, Samulski, Jade, Samulski, Richard Jude, Sigg, Daniel C, Weber, Thomas, Kranias, Evangelia G, Hajjar, Roger J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429688/
https://ncbi.nlm.nih.gov/pubmed/25023328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.127
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