Emerging Understanding of Bcl-2 Biology: Implications for Neoplastic Progression and Treatment

Bcl-2, the founding member of a family of apoptotic regulators, was initially identified as the protein product of a gene that is translocated and overexpressed in greater than 85% of follicular lymphomas (FLs). Thirty years later we now understand that Bcl-2 modulates the intrinsic apoptotic pathwa...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta
Main Authors: Correia, Cristina, Lee, Sun-Hee, Meng, X. Wei, Vincelette, Nicole D., Knorr, Katherine L.B., Ding, Husheng, Nowakowski, Grzegorz S., Dai, Haiming, Kaufmann, Scott H.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429517/
https://ncbi.nlm.nih.gov/pubmed/25827952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.03.012
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