Effects of inorganic iron and myoglobin on in vitro proximal tubular lipid peroxidation and cytotoxicity.

Recent in vivo studies suggest that heme Fe causes proximal tubular lipid peroxidation and cytotoxicity, thereby contributing to the pathogenesis of myoglobinuric (Mgb) acute renal failure. Because hydroxyl radical (.OH) scavengers [dimethylthiourea (DMTU), benzoate, mannitol] can mitigate this inju...

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Publicado en:	J Clin Invest
Autores principales:	Zager, R A, Foerder, C A
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1992
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442948/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1311724/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115682
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