Effects of inorganic iron and myoglobin on in vitro proximal tubular lipid peroxidation and cytotoxicity.

Recent in vivo studies suggest that heme Fe causes proximal tubular lipid peroxidation and cytotoxicity, thereby contributing to the pathogenesis of myoglobinuric (Mgb) acute renal failure. Because hydroxyl radical (.OH) scavengers [dimethylthiourea (DMTU), benzoate, mannitol] can mitigate this inju...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Zager, R A, Foerder, C A
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442948/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1311724/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115682
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