High-affinity insulin binding to an atypical insulin-like growth factor-I receptor in human breast cancer cells.

We studied the nature of insulin receptor binding in MCF-7 breast cancer cells. In both intact cells and solubilized receptor preparations, high-affinity insulin binding was seen. However, unlabeled insulin-like growth factor-I (IGF-I) was five-fold more potent in inhibiting 125I-insulin binding tha...

תיאור מלא

מידע ביבליוגרפי

הוצא לאור ב:	J Clin Invest
Principais autores:	Milazzo, G, Yip, C C, Maddux, B A, Vigneri, R, Goldfine, I D
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Clinical Investigation 1992
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442936/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1311720/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115670
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!