High-affinity insulin binding to an atypical insulin-like growth factor-I receptor in human breast cancer cells.

We studied the nature of insulin receptor binding in MCF-7 breast cancer cells. In both intact cells and solubilized receptor preparations, high-affinity insulin binding was seen. However, unlabeled insulin-like growth factor-I (IGF-I) was five-fold more potent in inhibiting 125I-insulin binding tha...

Descripció completa

Dades bibliogràfiques

Publicat a:	J Clin Invest
Autors principals:	Milazzo, G, Yip, C C, Maddux, B A, Vigneri, R, Goldfine, I D
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 1992
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442936/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1311720/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115670
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!